Skip to the content
Aletheia

Collapse, Not Computation · source record · paper

Quantum computation in brain microtubules: Decoherence and biological feasibility

Hagan, S.; Hameroff, S. R.; Tuszyński, J. A. · 2002

AI-verified citationSRC-HAGAN-2002
identifier / locator
Physical Review E 65(6): 061901. DOI: 10.1103/PhysRevE.65.061901
url
https://doi.org/10.1103/PhysRevE.65.061901
verification note
Verified via Crossref and PubMed (PMID 12188753); abstract read directly (2026-08-22 run). The revised decoherence estimate of 10⁻⁵–10⁻⁴ s and the eight enumerated objections are confirmed in the abstract.
reliability notes
  • Published in the same journal as the critique it answers — a real scientific exchange rather than a blog rebuttal.
  • Its central point is well taken and often missed: Tegmark modeled a soliton in superposition along the microtubule, not the superposed protein conformations of the Orch OR model, so the two calculations are not about the same physical state.
  • Even on its own numbers this does not reach Orch OR's requirement: 10⁻⁵–10⁻⁴ s is one to two orders of magnitude short of the ~25 ms gamma-band conscious moment the theory needs. Both papers are calculations; neither measured a living microtubule.

Evidence drawn from this source

Qualifies· moderateORCH-E008

Hagan, Hameroff & Tuszyński: revised estimate 10⁻⁵–10⁻⁴ s — still short of requirement

what the source states
The abstract states that the authors "critically examine the assumptions made in [Tegmark's] model and re-examine the decoherence times for superposed states of microtubule tubulins," and that "correction of Tegmark's assumptions yields decoherence times of 10⁻⁵ to 10⁻⁴ seconds" — up to seven to eight orders of magnitude longer than Tegmark's figures. The paper enumerates several specific objections, the most consequential being that Tegmark modeled a soliton in superposition along the microtubule rather than the superposed protein conformations of the Orch OR proposal.
what we infer
The central objection lands: the two papers computed decoherence for different physical states, so the seven-to-eight-order-of-magnitude gap between them is partly an artifact of modeling different things. That is a genuine correction and it is why "the brain is warm and wet, therefore no" is an inadequate argument. But this record is filed as `qualifies` rather than `supports` because even the proponents' own revised number does not reach their requirement: 10⁻⁵–10⁻⁴ s is one to two orders of magnitude short of the ~25 ms conscious moment the theory needs. Two calculations disagreeing by orders of magnitude, neither anchored to a measurement, is the actual state of this rung — and it is why ORCH-C010 is assessed as unresolved rather than refuted.
limitations
  • Also a calculation, not a measurement.
  • Authored by two of the theory's principals; not an independent reanalysis.
  • Even the favorable estimate falls one to two orders of magnitude short of the theory's own requirement.
  • The competing estimates have never been adjudicated by experiment, which is the only thing that would settle them.
Hagan, S. (2002)AI-verified citationORCH-C010