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State, Not Scar · source record · paper

The Hemo-Neural Hypothesis: On the Role of Blood Flow in Information Processing

Moore, C. I.; Cao, R. · 2008

AI-verified citationSRC-MOORE-CAO-2008
identifier / locator
Journal of Neurophysiology 99(5): 2035–2047. DOI: 10.1152/jn.01366.2006
verification note
Confirmed via Crossref (2026-08-22 batch). Accuracy correction to the essay: the co-author is Rosa Cao, not "Rosalind Cao."
reliability notes
  • A hypothesis paper, not an experimental demonstration: it proposes candidate mechanisms (mechanical, thermal, chemical) by which hemodynamics could modulate neural computation.

Evidence drawn from this source

Context· moderateVASO-E004

The hemo-neural hypothesis as proposed

what the source states
Moore and Cao propose that hemodynamics — blood flow and volume — may actively modulate neuronal information processing rather than merely supplying metabolic support, through candidate mechanical, thermal, and chemical pathways, and predict consequences for sensory gating and disease.
what we infer
The read path of the loop, stated as a hypothesis in 2008: this paper defines the claim rather than demonstrating it. The essay's "Rosalind Cao" should be Rosa Cao.
limitations
  • A hypothesis paper: proposes mechanisms, presents no new experimental demonstration.
Moore, C. I. (2008)AI-verified citationVASO-C012