Supports· moderateORCH-E044
Radical-pair spin dynamics modelled as a modulator of microtubule polymerization
- what the source states
- The authors insert magnetic-field and hyperfine effects into a two-rate kinetic model of tubulin polymerization, stating that "this rate is influenced by a RP reaction", and report that "Our model reproduces the experimental findings of Ref. 40 fairly well" — the reported disorder of tubulin assembly under a hypomagnetic field.
- what we infer
- My inference: this supplies a mechanistic rival to the 'general cellular disruption' reading of the same-direction stabilizer/destabilizer anomaly, and unlike that reading it carries field- and isotope-dependent predictions that can be tested.
- limitations
- Free parameters (recombination and relaxation rates) are chosen to reproduce the target ratio; the experiment being fitted reported no uncertainty, as the authors note.
- Same authors as SRC-SMITH-2021; not independent.
- No anesthesia endpoint is measured or modelled here.