Collapse, Not Computation · reading guide
Resources
Everything below is derived from this case's own source records — 46 of them — plus a small curated shelf of learning materials. Verification labels say exactly how much checking stands behind each record; nothing here is a recommendation to believe, only to read.
Primary literature32
Papers, preprints, and reports the case draws on — the records to read before trusting any summary, ours included.
- SRC-HUANG-2026paper · 2026
Brain-penetrant microtubule-stabilizer epothilone B delays isoflurane-induced unconsciousness in mice
Huang, Yixiang; Qiu, Zitong; Yu, Xinyue; Lee, Sophia; Zeng, Xiran; Chang, Abbie; Wiest, Michael C.
- SRC-ZAHAVY-2026paper · 2026
Position: LLMs can't jump
Zahavy, Tom; Google DeepMind
- SRC-GASSAB-2026preprint · 2026
Quantum Information Flow in Microtubule Tryptophan Networks
Lea Gassab; Onur Pusuluk; Travis J. A. Craddock
- SRC-GASSAB-2026Apreprint · 2026
Engineering quantum optical responses of microtubules through tryptophan-network simulations and ultraviolet spectroscopy
Lea Gassab; Travis J. A. Craddock
- SRC-WIEST-2025paper · 2025
A quantum microtubule substrate of consciousness is experimentally supported and solves the binding and epiphenomenalism problems
Wiest, Michael C.
- SRC-ZOGHI-2025paper · 2025
Dynamics of Delayed Luminescence in Tubulin and Microtubule Constructs: an Insight into Collective Radiative Effects
Zoghi, M.; Batarseh, M.; Wu, R.; Tuszynski, J. A.; Dogariu, A.
- SRC-WIEST-2025Apaper · 2025
Old theory, new evidence: inhalational anesthetics disrupt a collective quantum state of intraneuronal microtubules to cause unconsciousness
Michael C. Wiest
- SRC-BABCOCK-2024paper · 2024
Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological Architectures
Babcock, Nathan S.; Montes-Cabrera, Gabriel; Oberhofer, Kearnan E.; Chergui, Majed; Celardo, Gian Luca; Kurian, Philip
- SRC-KHAN-2024paper · 2024
Microtubule-Stabilizer Epothilone B Delays Anesthetic-Induced Unconsciousness in Rats
Khan, Sana; Huang, Yixiang; Timuçin, Derin; Bailey, Shantelle; Lee, Sophia; Lopes, Jessica; Gaunce, Emeline; Mosberger, Jasmine; Zhan, Michelle; Abdelrahman, Bothina; Zeng, Xiran; Wiest, Michael C.
- SRC-KALRA-2023paper · 2023
Electronic Energy Migration in Microtubules
Kalra, Aarat P.; Benny, Alfy; Travis, Sophie M.; Zizzi, Eric A.; Morales-Sanchez, Austin; Oblinsky, Daniel G.; Craddock, Travis J. A.; Hameroff, Stuart R.; MacIver, M. Bruce; Tuszyński, Jack A.; Petry, Sabine; Penrose, Roger; Scholes, Gregory D.
- SRC-MCQUEEN-2023paper · 2023
Have underground radiation measurements refuted the Orch OR theory?
McQueen, Kelvin J.
- SRC-ARNQUIST-2023paper · 2023
A Search for Spontaneous Radiation from Wavefunction Collapse in the Majorana Demonstrator
I. J. Arnquist; Majorana Collaboration
- SRC-KERSKENS-2023paper · 2023
Reply to Comment on: 'Experimental indications of non-classical brain function' (2022 Journal of Physics Communications 6 105001)
Christian Kerskens; David López Pérez
- SRC-KERSKENS-2022paper · 2022
Experimental indications of non-classical brain functions
Kerskens, Christian Matthias; López Pérez, David
- SRC-ZADEHHAGHIGHI-2022paper · 2022
Radical pairs may play a role in microtubule reorganization
Hadi Zadeh-Haghighi; Christoph Simon
- SRC-DISI-2022preprint · 2022
On the conjectured gravity-related collapse rate E_Δ/ħ of massive quantum superpositions
Lajos Diósi
- SRC-SMITH-2021paper · 2021
Radical pairs may play a role in xenon-induced general anesthesia
Jordan Smith; Hadi Zadeh-Haghighi; Dennis Salahub; Christoph Simon
- SRC-SAXENA-2020paper · 2020
Fractal, Scale Free Electromagnetic Resonance of a Single Brain Extracted Microtubule Nanowire, a Single Tubulin Protein and a Single Neuron
Saxena, Komal; Singh, Pushpendra; Sahoo, Pathik; Sahu, Satyajit; Ghosh, Subrata; Ray, Kanad; Fujita, Daisuke; Bandyopadhyay, Anirban
- SRC-HOWL-2019paper · 2019
Exploring the unification of quantum theory and general relativity with a Bose–Einstein condensate
Howl, Richard; Penrose, Roger; Fuentes, Ivette
AI-verified citationdoi.org ↗ - SRC-LI-2018paper · 2018
Nuclear Spin Attenuates the Anesthetic Potency of Xenon Isotopes in Mice: Implications for the Mechanisms of Anesthesia and Consciousness
Li, Na; Lu, Dongshi; Yang, Lei; Tao, Huan; Xu, Younian; Wang, Chenchen; Fu, Lisha; Liu, Hui; Chummum, Yatisha; Zhang, Shihai
- SRC-HAMEROFF-2018-EDITORIALpaper · 2018
Anesthetic Action and "Quantum Consciousness": A Match Made in Olive Oil
Hameroff, S. R.
- SRC-CRADDOCK-2017paper · 2017
Anesthetic Alterations of Collective Terahertz Oscillations in Tubulin Correlate with Clinical Potency: Implications for Anesthetic Action and Post-Operative Cognitive Dysfunction
Craddock, Travis J. A.; Kurian, Philip; Preto, Jordane; Sahu, Kamlesh; Hameroff, Stuart R.; Klobukowski, Mariusz; Tuszynski, Jack A.
- SRC-HELOU-2017paper · 2017
LISA pathfinder appreciably constrains collapse models
Bassam Helou; B. J. J. Slagmolen; David E. McClelland; Yanbei Chen
- SRC-LINGANNA-2015paper · 2015
Taxane modulation of anesthetic sensitivity in surgery for nonmetastatic breast cancer
Linganna, R. E.; Levy, W. J.; Dmochowski, I. J.; Eckenhoff, R. G.; Speck, R. M.
- SRC-HAMEROFF-PENROSE-2014paper · 2014
Consciousness in the universe: A review of the 'Orch OR' theory
Hameroff, Stuart; Penrose, Roger
AI-verified citationdoi.org ↗ - SRC-EMERSON-2013paper · 2013
Direct Modulation of Microtubule Stability Contributes to Anthracene General Anesthesia
Emerson, Daniel J.; Weiser, Brian P.; Psonis, John; Liao, Zhengzheng; Taratula, Olena; Fiamengo, Ashley; Wang, Xiaozhao; Sugasawa, Keizo; Smith, Amos B. III; Eckenhoff, Roderic G.; Dmochowski, Ivan J.
- SRC-CARHART-HARRIS-2012paper · 2012
Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin
Carhart-Harris, R. L.; Erritzoe, D.; Williams, T.; et al.
- SRC-EGER-2008paper · 2008
Is a new paradigm needed to explain how inhaled anesthetics produce immobility?
Eger, E. I. 2nd; Raines, D. E.; Shafer, S. L.; Hemmings, H. C. Jr; Sonner, J. M.
- SRC-JURD-2007paper · 2007
Mapping the contribution of β3-containing GABA-A receptors to volatile and intravenous general anesthetic actions
Zeller, A.; Arras, M.; Jurd, R.; Rudolph, U.
- SRC-JURD-2003paper · 2003
General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA_A receptor β3 subunit
Jurd, Rachel; Arras, Margarete; Lambert, Sachar; Drexler, Berthold; Siegwart, Roberta; Crestani, Florence; Zaugg, Michael; Vogt, Kaspar E.; Ledermann, Birgit; Antkowiak, Bernd; Rudolph, Uwe
- SRC-HAGAN-2002paper · 2002
Quantum computation in brain microtubules: Decoherence and biological feasibility
Hagan, S.; Hameroff, S. R.; Tuszyński, J. A.
- SRC-PENROSE-1996paper · 1996
On Gravity's role in Quantum State Reduction
Penrose, Roger
AI-verified citationdoi.org ↗
Critiques & counter-analyses10
Sources whose evidence in this case predominantly undermines the featured hypothesis. Read these with the same seriousness as the supporting work.
- SRC-SAWIN-2026preprint · 2026
An explicit lower bound for the unit distance problem
Sawin, Will
- SRC-ORCH-S001workpaper · 2026
Workpaper: the quantitative commitments of the Orch OR literature (study ORCH-S001)
Aletheia editorial AI (Kimi K3, Cursor cloud agent)
AI-verified citationUndermines ×1Qualifies ×1no public link on record - SRC-ORCH-S002workpaper · 2026
Workpaper: xenon isotope potency regressed on nuclear spin and atomic mass (study ORCH-S002)
This site (AI-authored project work held in the repository)
AI-verified citationSupports ×1Undermines ×2Qualifies ×1no public link on record - SRC-LI-2025paper · 2025
Microtubule-modulating drugs alter sensitivity to isoflurane in mice
Li, Na; You, Zerong; Ren, Yang; Kim, Hyung Hwan; Yang, Jinsheng; Li, Ge; Doheny, Jason T.; Ding, Weihua; Xia, Suyun; Wang, Shiyu; Chen, Lucy; Mao, Jianren; Martyn, J. A. Jeevendra
- SRC-HUBERT-2025paper · 2025
Olympiad-level formal mathematical reasoning with reinforcement learning
Hubert, Thomas; Mehta, Rishi; Sartran, Laurent; Horváth, Miklós Z.; Žužić, Goran; Wieser, Eric; Huang, Aja; Schrittwieser, Julian; Schroecker, Yannick; Masoom, Hussain
- SRC-WARREN-2023paper · 2023
Comment on: 'Experimental indications of non-classical brain function' 2022 Journal of Physics Communications 6 105001
Warren, Warren S.
- SRC-DERAKHSHANI-2022paper · 2022
At the crossroad of the search for spontaneous radiation and the Orch OR consciousness theory
Derakhshani, Maaneli; Diósi, Lajos; Laubenstein, Matthias; Piscicchia, Kristian; Curceanu, Catalina
- SRC-DONADI-2021paper · 2021
Underground test of gravity-related wave function collapse
Donadi, Sandro; Piscicchia, Kristian; Curceanu, Catalina; Diósi, Lajos; Laubenstein, Matthias; Bassi, Angelo
- SRC-REIMERS-2014paper · 2014
The revised Penrose–Hameroff orchestrated objective-reduction proposal for human consciousness is not scientifically justified
Reimers, Jeffrey R.; McKemmish, Laura K.; McKenzie, Ross H.; Mark, Alan E.; Hush, Noel S.
- SRC-TEGMARK-2000paper · 2000
Importance of quantum decoherence in brain processes
Tegmark, Max
Web & commentary4
Webpages, press, and commentary — useful for orientation, weak as evidence.
- SRC-OPENAI-UNITDIST-2026webpage · 2026
An OpenAI model has disproved a central conjecture in discrete geometry
OpenAI
- SRC-JHONG-ORCHOR-2026webpage · 2026
Orch OR Ascending: Primer 2020–2026
Jhong, Eugene; Strange Loops In My Head (Substack)
Verified — held in project libraryQualifies ×1no public link on record - SRC-JHONG-ERDOS-2026webpage · 2026
The Erdős Unit Distance Problem and Penrose 'Understanding': What might stay out of the reach of classical computational AI?
Jhong, Eugene; Strange Loops In My Head (Substack)
Verified — held in project libraryQualifies ×1no public link on record - SRC-DEEPMIND-IMO-2025webpage · 2025
Advanced version of Gemini with Deep Think officially achieves gold-medal standard at the International Mathematical Olympiad
Google DeepMind
grouping is derived: a source lands under “critiques” when its evidence records in this case predominantly undermine the featured hypothesis · every entry links to its full provenance record